Peer-reviewed literature on the CyberKnife® System is accumulating rapidly. Below is a list of papers published in respected medical journals describing CyberKnife treatment throughout the body, along with a brief summary for each. Click on the links to see each paper’s full reference and abstract located online (most on PubMed, a medical research search site maintained by the U.S. National Library of Medicine and the National Institutes of Health).

Lung

Fractionated stereotactic body radiation therapy in the treatment of primary, recurrent, and metastatic lung tumors: the role of positron emission tomography/computed tomography-based treatment planni Coon et al. 2008. University of Pittsburgh researchers treated a variety of patients with primary lung cancer, metastatic lung tumors, or recurrent cancer. Using the CyberKnife System they delivered 3 fractions of 20 Gy and concluded it was an effective treatment for patients with medically inoperable recurrent or metastatic lung cancer.
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CyberKnife radiosurgery for stage I lung cancer: results at 36 months. Brown et al. 2007 Miami researchers show that image-guided robotic stereotactic radiosurgery of lung tumors with the CyberKnife System in medically inoperable patients with early non-small-cell lung cancer (NSCLC) achieves excellent local disease control with limited toxicity to surrounding tissues and, in many cases, might be curative for patients for whom surgery is not an option
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Radical stereotactic radiosurgery with real-time tumor motion tracking in the treatment of small peripheral lung tumors. Collins et al 2007 Georgetown researchers used the CyberKnife System to deliver 45-60 Gy in 3 fractions to small tumors (including some metastatic tumors) in the outer lung, resulting in 83% local control and 84% overall survival at 12 months.

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