Peer-reviewed literature on the CyberKnife® System is accumulating rapidly. Below is a list of papers published in respected medical journals describing CyberKnife treatment throughout the body, along with a brief summary for each. Click on the links to see each paper’s full reference and abstract located online (most on PubMed, a medical research search site maintained by the U.S. National Library of Medicine and the National Institutes of Health).

Spine

CyberKnife stereotactic radiosurgical treatment of spinal tumors for pain control and quality of life. Degen, et al. 2005 Georgetown University Researchers performed CyberKnife System radiosurgery on patients with both benign and malignant spinal tumors. The results show pain relief and maintenance of quality of life after the treatment.
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CyberKnife radiosurgery for benign intradural extramedullary spinal tumors. Dodd et al. 2006 Stanford University researchers determined that benign lesions located on the spinal cord can be treated safely and effectively with the CyberKnife System.
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Multisession CyberKnife radiosurgery for intramedullary spinal cord arteriovenous malformations. Sinclair et al. 2006 Stanford University researchers used the CyberKnife System to treat spinal cord AVMs with fractionated stereotactic radiosurgery.
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CyberKnife radiosurgery for breast cancer spine metastases: a matched-pair analysis. Gagnon et al. 2007 Georgetown University researchers performed a comparison of external beam radiation therapy to CyberKnife System stereotactic radiosurgery for breast cancer metastasis to the spine.  Outcomes were statistically comparable, even though most of the patients treated with the CyberKnife System had previously undergone external beam radiation therapy.
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Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution. Gerszten et al. 2007: Researchers from the University of Pittsburgh Medical Center performed the largest published study on spinal radiosurgery. Their results show that single fraction CyberKnife System radiosurgery is safe and effective both as a primary treatment modality and as salvage treatment for spinal tumors.

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